Structural heart disease is characterized by an abnormality in one or more components of the heart, such as valves, muscles, walls, septum, and major arteries. Several patients do not experience any symptoms. However, subtle fatigue and chest pain may be warning signs. The types of structural heart diseases are valve regurgitation, stenosis, septal defects, hypertrophic obstructive cardiomyopathy, and coarctation of the aorta.